Enjoy fast, free delivery, exclusive deals, and award-winning movies & TV shows with Prime
Try Prime
and start saving today with fast, free delivery
Amazon Prime includes:
Fast, FREE Delivery is available to Prime members. To join, select "Try Amazon Prime and start saving today with Fast, FREE Delivery" below the Add to Cart button.
Amazon Prime members enjoy:- Cardmembers earn 5% Back at Amazon.com with a Prime Credit Card.
- Unlimited Free Two-Day Delivery
- Streaming of thousands of movies and TV shows with limited ads on Prime Video.
- A Kindle book to borrow for free each month - with no due dates
- Listen to over 2 million songs and hundreds of playlists
- Unlimited photo storage with anywhere access
Important: Your credit card will NOT be charged when you start your free trial or if you cancel during the trial period. If you're happy with Amazon Prime, do nothing. At the end of the free trial, your membership will automatically upgrade to a monthly membership.
$25.49$25.49 $15.93 per Fl Oz ($15.93$15.93 / Fl Oz)
Ships from: Amazon.com Sold by: Amazon.com
$24.22$24.22 $15.14 per Fl Oz ($15.14$15.14 / Fl Oz)
$21.67$21.67 ($13.54$13.54 / Fl Oz)
First delivery on May 21 FREE delivery Sunday, May 19 on orders shipped by Amazon over $35
Ships from: Amazon.com Sold by: Amazon.com
• No fees
• Cancel anytime
Unlock 15% savings
Save 15% when you receive 5 or more products in one auto-delivery to one address. Currently, you'll save 5% on your Aug 15 delivery.Choose how often it's delivered
From once every 2 weeks to once every 6 monthsSkip or cancel any time
We'll send you a reminder before each delivery.Potential Savings
Potential Yearly Savings is an estimate based on your selected delivery frequency and the base discount. Actual savings may change based on delivery frequency and discount eligibility.Pricing
While you will always receive a Subscribe & Save discount, individual product prices can go up or down over time. If the price of your subscribed product changes, the new price will be displayed in your order review email and will be applied only on future shipments. You can review your subscription price and edit or cancel your subscription at any timeAdded to cart
Add other items:
- 7 VIDEOS
Image Unavailable
Color:
-
-
-
- To view this video download Flash Player
Differin Acne Treatment Gel, 90 Day Supply, Retinoid Treatment For Face With 0.1% Adapalene, Gentle Skin Care For Acne Prone Sensitive Skin, 45G Pump
Learn more
Return this item for free
Free returns are available for the shipping address you chose. You can return the item for any reason in new and unused condition: no shipping charges
Learn more about free returns.- Go to your orders and start the return
- Select the return method
- Ship it!
Learn more
Learn more
Return this item for free
Free returns are available for the shipping address you chose. You can return the item for any reason in new and unused condition: no shipping charges
Learn more about free returns.- Go to your orders and start the return
- Select the return method
- Ship it!
Purchase options and add-ons
Skin Type | Combination, Acne Prone, Normal |
Product Benefits | Anti-Acne |
Use for | Face |
Scent | Unscented |
Special Ingredients | Retinoid |
About this item
- Clears breakouts where they start (Deep in pores) and prevents new acne from forming, which ultimately restores skin's texture and tone
- Clears breakouts where they start (Deep in pores) and prevents new acne from forming, which ultimately restores skin's texture and tone
- Adapalene was created for superior tolerability compared to other prescription retinoid products not containing Adapalene; It is suitable for use as part of your morning or evening regimen
- Water based formula, oil free, alcohol free, fragrance free, non comedogenic; Helps reduce the risk of scarring and Hyperpigmentation by treating Acne
- In a clinical study, Differin gel provided up to 87 percent reduction in acne breakouts after 12 weeks, which will continue to improve with further use
Customers usually keep this item
This product has fewer returns than average compared to similar products.
Frequently bought together
Top rated similar items
- Taro Adapalene 0.1% Acne Treatment Gel - Paraben Free (0.5oz)Amazon's Choicein Facial Cleansing Gels
From the brand
From the manufacturer
5% BPO Daily Cleanser | 10% BPO Acne Cleanser | Dark Spot Corrector Serum | 0.1% Adapalene Gel | Oil Absorbing Moisturizer | Acne-Prone Skin Patches | |
Customer Reviews
|
4.5 out of 5 stars
12,331
|
4.6 out of 5 stars
253
|
4.1 out of 5 stars
2,453
|
4.5 out of 5 stars
77,817
|
4.4 out of 5 stars
6,756
|
3.9 out of 5 stars
262
|
Price
| $9.91$9.91 | $10.79$10.79 | $16.21$16.21 | $13.99$13.99 | $12.79$12.79 | $9.99$9.99 |
Use for
| Deep Cleaning Pores | Quickly clearing acne | Reducing post-acne marks | Clearing, preventing acne | Hydrating sun protection | Shrinking imperfections |
Key ingredient
| 5% Benzoyl Peroxide | 10% Benzoyl Peroxide | 4% Niacinamide | 0.1% Adapalene | 5% Octisalate 7% Octocrylene | Salicylic Acid |
Target areas
| Face & Body | 10% Benzoyl Peroxide | Face | Face | Face | Face |
Skin type
| All Skin Types | Acne-prone | All Skin Types | Acne-prone | Oily Skin | All Skin Types |
| — | — | — | — | — | — |
Product Description
Differin Gel contains an Rx-strength acne-fighting retinoid. It clears breakouts where they start (deep in the pores), Prevents acne before it begins, and as a result, restores skin's texture and tone.
Product details
- Product Dimensions : 1.69 x 2.8 x 7 inches; 4 ounces
- Item model number : 0299.491040
- Department : Beauty & Personal Care
- UPC : 302994910403
- Manufacturer : Galderma
- ASIN : B07ZTN5N1V
- Country of Origin : Canada
- Best Sellers Rank: #43 in Beauty & Personal Care (See Top 100 in Beauty & Personal Care)
- #3 in Facial Masks
- Customer Reviews:
Product guides and documents
Videos
Videos for this product
0:48
Click to play video
DOES IT ACTUALLY HELP? Differin Acne Treatment Gel
Ryan
Videos for this product
2:01
Click to play video
My Experience: Acne Treatment Differin Gel
PD Reviews
Videos for this product
0:12
Click to play video
Acne hero products #skincare
Dr. Chris Tomassian's Skincare Must-Haves
Videos for this product
0:10
Click to play video
Unboxing Differin Gel I love this stuff!
Simply Mary
Videos for this product
1:43
Click to play video
How to use
Galderma Laboratories Inc
Videos for this product
3:33
Click to play video
Customer Review: Use after moisturizer to help irritation!
Portia Scott.
Videos for this product
0:25
Click to play video
Customer Review: Changed my skin within 4 weeks
Alexis
Important information
Safety Information
For external use only. Do not use on damaged skin (cuts, abrasions, eczema, sunburn). Do not use if you are allergiv to adapalene or any of the ingredients in this product. If pregnant or breast-feeding, ask a doctor before use. When using this product limit sun exposure, including light from tanning beds, and use sunscreen outdoors. Do not wax to remove hair in areas where the product has been applied. During the early weeks of use, your acne may appear to worsen before it improves (this is normal); continue as directed, unless you get irritation that becomes severe.
Indications
Face
Ingredients
Active Ingredients: Adapalene (0.1%)(Retinoid). Purpose: Acne Treatment, Read Consumer Information Leaflet. Inactive Ingredients: Carbomer 940, Edetate Disodium, Methylparaben, Poloxamer 182, Propylene Glycol, Purified Water and Sodium Hydroxide, May Contain Hydrochloric Acid to Adjust pH.
Directions
Adults and children 12 years of age and older:- Use once daily- Clean the skin gently and pat dry before applying the product- Cover the entire affected area with a thin layer. For example, if your acne is on the face, apply the product to the entire face.- Do not use more than one time a day. Applying more than directed will not provide faster or better results, but may worsen skin irritation.C
Looking for specific info?
Customer reviews
Customer Reviews, including Product Star Ratings help customers to learn more about the product and decide whether it is the right product for them.
To calculate the overall star rating and percentage breakdown by star, we don’t use a simple average. Instead, our system considers things like how recent a review is and if the reviewer bought the item on Amazon. It also analyzed reviews to verify trustworthiness.
Learn more how customers reviews work on AmazonReviews with images
-
Top reviews
Top reviews from the United States
There was a problem filtering reviews right now. Please try again later.
I had the MOST TERRIBLE acne. No, I'm not talking about a small tiny excuse of a blemish that your friend with great skin complains about when she has her "bad skin" days. My face was RED and PAINFUL. My cheeks were COVERED all the time, and I had no area on my face where acne wouldn't pop up. Nose, brows, chin, jaw, underneath the jaw, you name it. I had tried Curology and while my skin got amazing for the first 6 months, my acne returned with a VENGEANCE. I had tried so many things, clay masks, benzoyl peroxide, salicylic acid, other AHAs and BHAs, sulfur, rosehip oil, and even supplements like zinc and milk thistle, you name it. Nothing worked at all. I was so so embarrassed of my skin, but I couldn't wear makeup either since makeup made my acne SO MUCH worse.
I heard about Differin and I figured "well, might as well give this a try cause it can't get any worse". Boy, I was wrong. It did get worse. Much worse. Suddenly I had SO much more acne and I felt like crap. I couldn't believe my skin could get worse, but it did. Differin was the only thing I was using so I knew this was it. I was depressed but I stuck with it, cause I wanted to test it for at least 4 months. I thought I might as well test the claim, since my skin is so bad already.
The first month was really really bad. It brought all underlying acne to the surface i.e. the purge phase. It did the purging for 3-4 months, but the first month was THE WORST. Not gonna lie to you, that first month will probably be the worst skin you've had in your life. Your skin will become SO SENSITIVE! Anticipate that! My skin has never been sensitive to products but while using this, my regular moisturizers and masks would sting like crazy (get stuff with no fragrance/alcohol or acids!). It didn't affect my skin in any other way, it just stung a lot. Oh, and I used to get my upper lip and brows waxed. Not with this you can't, the wax will tear off your skin since it gets much more sensitive. I learned the hard way. ONLY do threading!
However, after I waited out the terrible, terrible first month, I slowly began to see improvements. Marginal, though. I had acne, but I probably had just a tad less. And it continued that way, it kept improving. Eventually, my skin was so much clearer than before! I still had acne, mind you, it's not a miracle drug, but it was few and far in between. There would be times when I had no active acne, which was HUGE for me!! My face usually looked like a connect the dots game. However, I did hit a plateau. This worked phenomenally at reducing my ugly acne all over my face to a few zits here and there, however, my issue was deeper than that. Eventually, I went to a doctor and got on spironolactone.
Now, I am both on my Spiro and this. The combo of these two have made my skin so clear! I could have never imagined this day! I still need to use this, I have noticed my Spiro is not enough to keep zits at bay and if I skip a couple of nights putting on differin, new zits come up. I am so much happier now that I don't have zillions of gross zits on my face. I still get zits if I eat sugar or near my period but man, I am a long way from before! I have a few blemishes left over from before but I honestly don't care, my skin looks wayyy better. I can hide my blemishes with a sheer foundation of spot concealing if I want.
So if you've read till the end, the lesson is: be PATIENT and be realistic! Your acne did not appear overnight and will not disappear overnight. If you stick with this, it WILL work. However, your mileage may vary. My acne was extremely bad, so after I hit my "acne plateau" I went to the doctor. If your acne is not as bad, it's likely differin is all you need for clear skin! If you're on the fence, confused, depressed, frustrated and/or can't afford a doctor, it's worth a shot! Just be patient and gentle with your skin!
I will update this with pics of before and after when I have time. I used the sandwich method for application (moisturizer, differin, more moisturizer)
1st week: only used once. Didn’t notice any difference after. Also tried eating cleaner (more veggies, fruit, water)
2nd week: used 3 times (M, W, F) . Noticed a few new break outs but they cleared quickly
3rd week: used 3 times. Noticed new breakouts, some cystic painful ones in areas I would normally break out but even those cleared within a week. This was probably the worst week. But I’m finding old scars are fading a bit.
4th week: Cystic breakouts from last week have drained. Today is first day I have no new breakouts! Just some left over marks and old ones still drying up. I can see clear skin within my future! So happy with results.
I may try to bump up my use to 4 or 5 days now that my skin is tolerating it well and cut back if I notice any irritation or dryness. Will update soon!
I chose to go with Differin because of the stability of the molecules to be able to wear it both day and night. I also liked the fact it was as close to the prescription strength without having the medical bill. The price point was also a nice bonus!
These pictures are only 2 weeks apart! I don’t think I could have achieved these results without Differin as part of my routine!!
Reviewed in the United States on May 11, 2024
I chose to go with Differin because of the stability of the molecules to be able to wear it both day and night. I also liked the fact it was as close to the prescription strength without having the medical bill. The price point was also a nice bonus!
These pictures are only 2 weeks apart! I don’t think I could have achieved these results without Differin as part of my routine!!
Don't:
1) Don't use on raw EXFOLIATED skin. Wait a couple days after exfoliating.
2) Don't use a SUDSING cleansing soap prior. Use a mild hydrating Cleanser.
3) Don't use after getting your skin waxed or shaved.
4) Avoid hot water and steam before use.
5) Do NOT go stand in the sun after applying (retin works by thinning the top layer of your skin which is usually used for protection against the sun). Don't take your chances!
6) do not apply to eyelids or neck or other thin skin areas including the inside of your wrists. You can apply Vaseline to these areas if needed to protect them.
7) don't freak out if your face flakes and don't scrub the flakes off. Moisturizer is your friend.
8) don't scratch at your skin if itches or burns, stay calm, rinse it off with cool water. Apply a gentle cream and then apply a cool wash cloth. Consider diluting before using again.
9) don't assume because your neighbor next door can use twice a day on fresh scrubbed skin with no adverse effects, that the same will be true for you. Adverse skin reactions can take weeks or months to heal from.
10) do NOT apply generously all over your skin. Pea size only on face.
Do:
1) plan on using once or twice a week at first for the first month. Remember "sparingly" is your motto.
2) Have a natural moisture barrier on your face first. Be sure you have not scrubbed your skin raw or clean prior and make sure face is danp prior to applying.
3) if you have ultra sensitive skin, apply a gentle moisturizer FIRST before applying differin. Allow to dry before applying differin.
4) do apply a creamy moisturizer after if needed. Wait five minutes before you do.
5) do also apply sunscreen RELIGIOUSLY if you will be outdoors. So important!!!!
6) do research "purging" and what you can do to minimize or avoid it.
7) do remember that this product is a MEDICATION and not your typical OTC cream. Use sparingly and with caution.
8) do remember that moisture is your friend. After cleansing, avoid drying your skin with towels. Avoid air drying as well.
9) do remember that with this product "less is more". It is potent stuff! Once or twice a week treatments alone will make a difference.
10) keep a good repair Cream on hand in possible event of harsh reaction or irritated skin. I recommend "first aid beauty ultra repair cream". This stuff is amazing. Hydrocortisone cream can also be used.
MOST IMPORTANTLY: it takes 6-12 weeks of patient and measured use before seeing positive long term results for acne. It can take up to a year before seeing positive results for aged and wrinkled skin.
MY RESULTS:
I started out at a twice a week and had no reaction except for mild redness, itching and tingling the following two days afterwards. When I tried to increase to three days a week, I started having issues. The solution to this was to revamp my skin care routine (listed below). After that, I was able to switch pretty rapidly to nightly use. The GAME CHANGER was adding First Aid Ultra Hydrating Cream.
I've included my before and six week after photos. My acne is gone and my pores most definitely shrunk. I used the same room and lighting and I notice that my skin has become much brighter and lighter. My guess is in removing the thing top layer of skin, we no longer see the old tanned skin I had. So far, I am happy with the results.
I am 38 years old. My long term goal is to prevent deep wrinkles and shrink my pores and hopefully reduce white Milia bumps under my eyes as well as all random acne and age spots. I know from researching this can take months and years so I'm feeling patient.
MY CURRENT DIFFERIN APPLICATION:
My morning routine:
- CereVe Hydrating Cleanser
- After rinsing, I apply Timewise Vitamin C Serum with the added F acid.
- Then, I apply a thin layer of Sunscreen: La Roche-Posay Anthelios with Mexoryl SX
OR CeraVe SPF 30.
*note: I believe the Vitamin C Serum helped with quicker skin cell turnover rate to prevent purging.
In the evenings:
- I double cleanse: first I use Yes To Coconuts Uktra Hydrating Creme Cleanser. After I rinse that off, I cleanse with CeraVe Hydrating Facial Cleanser.
- I allow skin to stay damp.
- I then apply a pea size amount of differin to my face (never on neck or eyelids).
- after about minutes, I follow that with First Aid Beauty Ultra Repair Cream.
- I apply CeraVe Skin renewing Serum to my eyes and neck and chest.
- note: I only use retin A products at night to decrease sun sensitivity. In the mornings, I use all my other acids and Vitamin C.
Be aware that most of the negative reviews on here are mostly due to user error and lack of knowledge in the product. There is no reason to have terrible breakouts or harm your skin. I'm horrified people are using this on their NECK right away. Poor skin! This is a potent product.
Good luck!
Reviewed in the United States on January 1, 2018
Don't:
1) Don't use on raw EXFOLIATED skin. Wait a couple days after exfoliating.
2) Don't use a SUDSING cleansing soap prior. Use a mild hydrating Cleanser.
3) Don't use after getting your skin waxed or shaved.
4) Avoid hot water and steam before use.
5) Do NOT go stand in the sun after applying (retin works by thinning the top layer of your skin which is usually used for protection against the sun). Don't take your chances!
6) do not apply to eyelids or neck or other thin skin areas including the inside of your wrists. You can apply Vaseline to these areas if needed to protect them.
7) don't freak out if your face flakes and don't scrub the flakes off. Moisturizer is your friend.
8) don't scratch at your skin if itches or burns, stay calm, rinse it off with cool water. Apply a gentle cream and then apply a cool wash cloth. Consider diluting before using again.
9) don't assume because your neighbor next door can use twice a day on fresh scrubbed skin with no adverse effects, that the same will be true for you. Adverse skin reactions can take weeks or months to heal from.
10) do NOT apply generously all over your skin. Pea size only on face.
Do:
1) plan on using once or twice a week at first for the first month. Remember "sparingly" is your motto.
2) Have a natural moisture barrier on your face first. Be sure you have not scrubbed your skin raw or clean prior and make sure face is danp prior to applying.
3) if you have ultra sensitive skin, apply a gentle moisturizer FIRST before applying differin. Allow to dry before applying differin.
4) do apply a creamy moisturizer after if needed. Wait five minutes before you do.
5) do also apply sunscreen RELIGIOUSLY if you will be outdoors. So important!!!!
6) do research "purging" and what you can do to minimize or avoid it.
7) do remember that this product is a MEDICATION and not your typical OTC cream. Use sparingly and with caution.
8) do remember that moisture is your friend. After cleansing, avoid drying your skin with towels. Avoid air drying as well.
9) do remember that with this product "less is more". It is potent stuff! Once or twice a week treatments alone will make a difference.
10) keep a good repair Cream on hand in possible event of harsh reaction or irritated skin. I recommend "first aid beauty ultra repair cream". This stuff is amazing. Hydrocortisone cream can also be used.
MOST IMPORTANTLY: it takes 6-12 weeks of patient and measured use before seeing positive long term results for acne. It can take up to a year before seeing positive results for aged and wrinkled skin.
MY RESULTS:
I started out at a twice a week and had no reaction except for mild redness, itching and tingling the following two days afterwards. When I tried to increase to three days a week, I started having issues. The solution to this was to revamp my skin care routine (listed below). After that, I was able to switch pretty rapidly to nightly use. The GAME CHANGER was adding First Aid Ultra Hydrating Cream.
I've included my before and six week after photos. My acne is gone and my pores most definitely shrunk. I used the same room and lighting and I notice that my skin has become much brighter and lighter. My guess is in removing the thing top layer of skin, we no longer see the old tanned skin I had. So far, I am happy with the results.
I am 38 years old. My long term goal is to prevent deep wrinkles and shrink my pores and hopefully reduce white Milia bumps under my eyes as well as all random acne and age spots. I know from researching this can take months and years so I'm feeling patient.
MY CURRENT DIFFERIN APPLICATION:
My morning routine:
- CereVe Hydrating Cleanser
- After rinsing, I apply Timewise Vitamin C Serum with the added F acid.
- Then, I apply a thin layer of Sunscreen: La Roche-Posay Anthelios with Mexoryl SX
OR CeraVe SPF 30.
*note: I believe the Vitamin C Serum helped with quicker skin cell turnover rate to prevent purging.
In the evenings:
- I double cleanse: first I use Yes To Coconuts Uktra Hydrating Creme Cleanser. After I rinse that off, I cleanse with CeraVe Hydrating Facial Cleanser.
- I allow skin to stay damp.
- I then apply a pea size amount of differin to my face (never on neck or eyelids).
- after about minutes, I follow that with First Aid Beauty Ultra Repair Cream.
- I apply CeraVe Skin renewing Serum to my eyes and neck and chest.
- note: I only use retin A products at night to decrease sun sensitivity. In the mornings, I use all my other acids and Vitamin C.
Be aware that most of the negative reviews on here are mostly due to user error and lack of knowledge in the product. There is no reason to have terrible breakouts or harm your skin. I'm horrified people are using this on their NECK right away. Poor skin! This is a potent product.
Good luck!
Top reviews from other countries
Reviewed in Australia on May 5, 2024
Disclaimer: While we work to ensure that product information is correct, on occasion manufacturers may alter their ingredient lists. Actual product packaging and materials may contain more and/or different information than that shown on our Web site. We recommend that you do not solely rely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. For additional information about a product, please contact the manufacturer. Content on this site is for reference purposes and is not intended to substitute for advice given by a physician, pharmacist, or other licensed health-care professional. You should not use this information as self-diagnosis or for treating a health problem or disease. Contact your health-care provider immediately if you suspect that you have a medical problem. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease or health condition. Amazon.com assumes no liability for inaccuracies or misstatements about products.